TY  -  JOUR
AU  -  Barbagelata, Elena
AU  -  Cilloniz, Catia
AU  -  Nicolini, Antonello
AU  -  Moretti, Anna Maria
T1  -  Sex differences in asthma and immunological response: 
an overview
PY  -  2019
Y1  -  2019-05-01
DO  -  10.1723/3188.31665
JO  -  The Italian Journal of Gender-Specific Medicine
JA  -  Ital J Gender-Specific Med
VL  -  5
IS  -  2
SP  -  68
EP  -  73
PB  -  Il Pensiero Scientifico Editore
SN  -  2612-3487
Y2  -  2026/05/24
UR  -  http://dx.doi.org/10.1723/3188.31665
N2  -  Summary. Gender differences in asthma incidence, prevalence and clinical phenotypes have been extensively reported worldwide. A number of studies have shown that respiratory allergy, and especially asthma, is prevalent in males during childhood, whereas it becomes more frequent and severe in females between adolescence and adulthood, suggesting that sex hormones play a role as important modulators of immune response. The mechanisms underlying these differences between females and males are most likely the effects on the immune and inflammatory responses of female hormones and the result of the activity of various cells and cytokines. Understanding gender differences in respiratory allergies and asthma is important for providing effective education and personalized management plans for patients throughout their lives.
ER  -