TY  -  JOUR
AU  -  Bellini, Arianna
AU  -  Rosa, Alessandro C
AU  -  Ferroni, Eliana
AU  -  Marino, Maria Lucia
AU  -  Finocchietti, Marco
AU  -  Masiero, Lucia
AU  -  Fiaschetti, Pamela
AU  -  Cardillo, Massimo
AU  -  Pierobon, Silvia
AU  -  Mazzone, Arianna
AU  -  Leoni, Olivia
AU  -  Ledda, Stefano
AU  -  Garau, Donatella
AU  -  Belleudi, Valeria
AU  -  CESIT study group
T1  -  Sex differences in immunosuppressive maintenance therapy and incidence of outcomes in kidney transplant recipients
PY  -  2024
Y1  -  2024-01-01
DO  -  10.1723/4235.42102
JO  -  Journal of Sex- and Gender-Specific Medicine
JA  -  J Sex Gender Specif Med
VL  -  10
IS  -  1
SP  -  23
EP  -  28
PB  -  Il Pensiero Scientifico Editore
SN  -  2974-8623
Y2  -  2026/04/15
UR  -  http://dx.doi.org/10.1723/4235.42102
N2  -  Summary. A multicentre retrospective observational study was conducted to analyse immunosuppressive regimens and outcomes by sex in incident patients who underwent kidney transplantation between 2009 and 2019. A total of 4,029 kidney recipients, 35.5% of whom were female, were considered. Immunosuppressive regimens were similar between male and female patients, with the most commonly prescribed regimen being tacrolimus + mycophenolate + steroids. Females had a higher risk of infection compared to males (HR = 1.33; 1.16-1.53), but no differences were observed for other outcomes. Further research is needed to understand the influence of sex and hormones on drug responses in order to tailor pharmacological treatment across different life stages.
ER  -