TY  -  JOUR
AU  -  Lodi, Elisa
AU  -  Rodighiero, Eleonora
AU  -  Poli, Maria Luisa
AU  -  Reggianini, Letizia
AU  -  Modena, Maria Grazia
T1  -  Optimal pharmacotherapy for hypertension in women: gender and ethnic differences in personalized medicine. A narrative review
PY  -  2025
Y1  -  2025-05-01
DO  -  10.1723/4533.45356
JO  -  Journal of Sex- and Gender-Specific Medicine
JA  -  J Sex Gender Specif Med
VL  -  11
IS  -  2
SP  -  87
EP  -  94
PB  -  Il Pensiero Scientifico Editore
SN  -  2974-8623
Y2  -  2026/05/01
UR  -  http://dx.doi.org/10.1723/4533.45356
N2  -  Summary. Arterial hypertension (AH) is the primary modifiable risk factor for cardiovascular disease (CVD), which is the leading cause of death among women worldwide. AH may affect men and women differently and recent advancements in this field have allowed for the identification of sex-related heterogeneities in clinical presentation, prevention, treatment, and prognosis. Recognizing these sex and gender disparities in AH is crucial for preventing CVD and tailoring treatment for women. Since CVD is substantially preventable, this review aims to provide an overview of AH prevention and management in women. Achieving optimal pharmacotherapy for AH in women poses several challenges due to various factors, including hormonal fluctuations, pregnancy considerations and potential side effects of antihypertensive medications. As the population ages, it becomes increasingly important to understand how sex and gender influence the prevalence, diagnosis, and management of AH, as its impact on women’s health and socioeconomic burden is expected to rise.
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